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Article

Mcm10 self-association is mediated by an N-terminal coiled-coil domain.

PloS one - 1 Jan 2013

Du Wenyue, Josephrajan Ajeetha, Adhikary Suraj, Bowles Timothy, Bielinsky Anja-Katrin, Eichman Brandt F

Abstract excerpt

Minichromosome maintenance protein 10 (Mcm10) is an essential eukaryotic DNA-binding replication factor thought to serve as a scaffold to coordinate enzymatic activities within the replisome. Mcm10 appears to function as an oligomer rather than in its monomeric form (or rather than as a monomer). However, various orthologs have been found to contain 1, 2, 3, 4, or 6 subunits and thus, this issue has remained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23894664
DOI: 10.1371/journal.pone.0070518
PMCID: PMC3720919

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