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Article

Mutation types and aging differently affect revertant fiber expansion in dystrophic mdx and mdx52 mice.

PloS one - 1 Jan 2013

Echigoya Yusuke, Lee Joshua, Rodrigues Merryl, Nagata Tetsuya, Tanihata Jun, Nozohourmehrabad Ashkan, Panesar Dharminder, Miskew Bailey, Aoki Yoshitsugu, Yokota Toshifumi

Abstract excerpt

Duchenne muscular dystrophy (DMD), one of the most common and lethal genetic disorders, and the mdx mouse myopathies are caused by a lack of dystrophin protein. These dystrophic muscles contain sporadic clusters of dystrophin-expressing revertant fibers (RFs), as detected by immunohistochemistry. RFs are known to arise from muscle precursor cells with spontaneous exon skipping (alternative splicing) and clonally...

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Source

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Identifiers

PMID: 23894429
DOI: 10.1371/journal.pone.0069194
PMCID: PMC3722172

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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