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Article

Impact of genetic variants of IL-6, IL6R, LRP5, ESR1 and SP7 genes on bone mineral density in postmenopausal Mexican-Mestizo women with obesity.

Gene - 10 Oct 2013

Méndez Juan Pablo, Rojano-Mejía David, Coral-Vázquez Ramón Mauricio, Coronel Agustín, Pedraza Javier, Casas María José, Soriano Ruth, García-García Eduardo, Vilchis Felipe, Canto Patricia

Abstract excerpt

BACKGROUND: Since obesity and osteoporosis present a high genetic predisposition and polymorphisms of IL-6, IL6R, LRP5, ESR1 and SP7 may influence the risk of both diseases, the aim of this study was to analyze the possible association of polymorphisms in these genes, as well as their haplotypes, with BMD variations in postmenopausal Mexican-Mestizo women with grade 2 or grade 3 obesity. METHODS: One hundred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23891823
DOI: 10.1016/j.gene.2013.07.008

Genes

ESR1
LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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