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Article

Trismus following radiotherapy to the head and neck is likely to have distinct genotype dependent cause.

Oral oncology - 1 Sept 2013

Lyons Andrew J, Crichton Siobhan, Pezier Thomas

Abstract excerpt

OBJECTIVES: Trismus frequently occurs as a consequence of radiotherapy or chemo-radiotherapy to the head and neck, with a loss of function that can reduce the overall quality of life. Radiation can trigger an intense fibrosis within the masticatory muscles and transforming growth factor beta 1 (TGF β1) is involved in this process. As in other tissues the degree of fibrosis may be related to a single nucleotide...

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Identifiers

PMID: 23891529
DOI: 10.1016/j.oraloncology.2013.05.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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