Article
Performance comparison of an in-house integrase genotyping assay versus the ViroSeq™ Integra48, and study of HIV-1 integrase polymorphisms in Hong Kong.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2013
To Sabrina Wai-Chi, Chen Jonathan Hon-Kwan, Wong Ka-Hing, Chan Kenny Chi-Wai, Ng Hon-Man, Wu Hao, Lam Jason Tszhin, Yam Wing-Cheong
Abstract excerpt
BACKGROUND: Integrase inhibitors are recently prescribed to multi-class drug resistant HIV-1 patients in Hong Kong. Unlike pol gene, there are no FDA-approved genotypic resistance tests available for int. Limited studies compared the performance between an in-house and commercial integrase genotyping system. Information on baseline polymorphisms was also insufficient in our region. OBJECTIVES: To compare...
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