Article
Clinical utility of genotyping resistance test on determining the mutation patterns in HIV-1 CRF01_AE and subtype B patients receiving antiretroviral therapy in Hong Kong.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2006
Yam W C, Chen J H K, Wong K H, Chan K, Cheng V C C, Lam H Y, Lee S S, Zheng B J, Yuen K Y
Abstract excerpt
BACKGROUND: HIV-1 genotypic resistance test (GRT) has been widely used to monitor HIV infection but only few reports revealed the mutation patterns of non-B HIV-1 subtypes. OBJECTIVE: To evaluate the concordance of GRT and clinical treatment outcomes on different HIV-1 subtypes and monitor the mutation patterns and frequencies. STUDY DESIGN: Pre- and post-treatment plasma samples from 123 patients (39 treatment...
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