Article
Interactive effect of bisphenol A (BPA) exposure with -22G/C polymorphism in LOX gene on the risk of osteosarcoma.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Jia Jie, Tian Qing, Liu Yong, Shao Zeng-Wu, Yang Shu-Hua
Abstract excerpt
BACKGROUND: Osteosarcomas have many established risk factors, both genetic and environmental, but by themselves these explain only part of the total cancer incidence. Bisphenol A (BPA) is an environmental estrogen associated with risk of several kinds of tumour. The lysyl oxidase gene (LOX) may also contribute to risk of tumours including osteosarcomas. Here, we investigated possible interactions of BPA and a LOX...
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