Article
Genetic polymorphisms of interleukin-1 beta and osteosarcoma risk.
International orthopaedics - 1 Aug 2014
He Yu, Liang XinJun, Meng ChunQing, Shao ZengWu, Gao Yong, Wu Qiang, Liu JianXiang, Wang Hong, Yang ShuHua
Abstract excerpt
PURPOSE: Osteosarcoma is the most common childhood bone cancer. Interleukin-1 beta (IL-1B) is crucially involved in osteosarcoma carcinogenesis. Whether genetic polymorphisms of IL-1B also influence osteosarcoma risk is unknown. The aim of this study was to investigate the association between IL-1B gene polymorphisms and osteosarcoma risk in Chinese Han patients. METHODS: A hospital-based case-control study...
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