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Article

Ultrarapid BRAF mutation detection on supernatant cell-free DNA obtained by FNA: An accurate and expedient method for BRAF assessment in aggressive thyroid carcinomas.

Cancer cytopathology - 1 May 2026

Gutierrez Amezcua Jose Manuel, Arcila Maria E, Ng Dianna L, Feratovic Rusmir, Bilal Khawaja Hasan, Cohen Jean Marc, Wei Xiao-Jun, Kezlarian-Sachs Brie, Sigel Carlie S, Agaram Narasimhan, Nafa Khedoudja, Salazar Paulo, Lin Oscar, Kim David

Abstract excerpt

BACKGROUND: For patients with aggressive thyroid cancer, including anaplastic thyroid carcinoma (ATC) and high-grade follicular cell-derived non-anaplastic thyroid carcinoma, rapid BRAF p.V600E testing is critical as targeted therapy with BRAF/MEK inhibitors significantly improves outcomes. This study assesses the performance and turnaround time (TAT) of the Biocartis Idylla platform for ultrarapid BRAF p.V600E...

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Share to Biomarkers, Tumor
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell-Free Nucleic Acids

Share to DNA Mutational Analysis

Share to High-Throughput Nucleotide Sequencing

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Carcinoma, Anaplastic

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Source

Open in PubMed Open full text

Identifiers

PMID: 42018428
DOI: 10.1002/cncy.70098
PMCID: PMC13102139

Genes

BRAF
TAT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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