Genetics of lipid traits and relationship to coronary artery disease.

doi:10.1007/s11886-013-0396-9

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Article

Genetics of lipid traits and relationship to coronary artery disease.

Current cardiology reports - 1 Sept 2013

Keenan Tanya E, Rader Daniel J

Abstract excerpt

Despite the critical importance of plasma lipoproteins in the development of atherosclerosis, varying degrees of evidence surround the causal associations of lipoproteins with coronary artery disease (CAD). These causal contributions can be assessed by employing genetic variants as unbiased proxies for lipid levels. A relatively large number of low-density lipoprotein cholesterol (LDL-C) variants strongly...

Topics

Biomarkers
Cholesterol, LDL
Coronary Artery Disease
Genetic Loci
Genetic Predisposition to Disease
Humans
Lipids
Lipoprotein(a)
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Triglycerides

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Identifiers

PMID: 23881580
DOI: 10.1007/s11886-013-0396-9
PMCID: PMC3883430

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