Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain.

Acta neuropathologica - 1 Oct 2013

Smolders Joost, Remmerswaal Ester B M, Schuurman Karianne G, Melief Jeroen, van Eden Corbert G, van Lier René A W, Huitinga Inge, Hamann Jörg

Abstract excerpt

Immune surveillance of the central nervous system (CNS) by T cells is important to keep CNS-trophic viruses in a latent state, yet our knowledge of the characteristics of CNS-populating T cells is incomplete. We performed a comprehensive, multi-color flow-cytometric analysis of isolated T cells f...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autopsy
Share to CD4-CD8 Ratio
Share to Corpus Callosum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-7

Share to Interleukin-7 Receptor alpha Subunit

Share to Receptors, CXCR3

Share to Receptors, Interleukin-8A

Share to Tissue Banks

Source

Identifiers

PMID: 23880787
DOI: 10.1007/s00401-013-1155-0

Genes

CXCR3
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23880787-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain.PMID 23880787Read ↗

Legend or Truth: Mature CD4+CD8+ Double-Positive T Cells in the Periphery in Health and DiseaseSemantic proximity Read ↗

Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS injury and viral infectionSemantic proximity Read ↗

NK cells in central nervous system disorders.Semantic proximity Read ↗

Tissue-resident CD8 T cells in central nervous system inflammatory diseases: present at the crime scene and …guiltySemantic proximity Read ↗

The Era of Cytotoxic CD4 T CellsSemantic proximity Read ↗

Peripheral human CD4+CD8+ T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15.Semantic proximity Read ↗

Brain Resident Memory T Cells Rapidly Expand and Initiate Neuroinflammatory Responses Following CNS Injury and Viral InfectionSemantic proximity Read ↗

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in femalesSemantic proximity Read ↗

Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patientsSemantic proximity Read ↗

Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue SyndromeSemantic proximity Read ↗

Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neuronsSemantic proximity Read ↗

Analysis of CD4+ CD8+ double-positive T cells in blood, cerebrospinal fluid and multiple sclerosis lesions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.