Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt Ligands Differentially Regulate Toxicity and Translocation of Graphene Oxide through Different Mechanisms in Caenorhabditis elegans.

Scientific reports - 13 Dec 2016

Zhi Lingtong, Ren Mingxia, Qu Man, Zhang Hanyu, Wang Dayong

Abstract excerpt

In this study, we investigated the possible involvement of Wnt signals in the control of graphene oxide (GO) toxicity using the in vivo assay system of Caenorhabditis elegans. In nematodes, the Wnt ligands, CWN-1, CWN-2, and LIN-44, were found to be involved in the control of GO toxicity. Mutation of cwn-1 or lin-44 gene induced a resistant property to GO toxicity and resulted in the decreased accumulation of GO...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycoproteins

Share to Intestinal Mucosa

Share to Oxides

Share to Permeability

Share to Reactive Oxygen Species

Share to Wnt Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 27958363
DOI: 10.1038/srep39261
PMCID: PMC5153639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt Ligands Differentially Regulate Toxicity and Translocation of Graphene Oxide through Different Mechanisms in Caenorhabditis elegans.PMID 27958363Read ↗

Functional disruption in epidermal barrier enhances toxicity and accumulation of graphene oxide.Semantic proximity Read ↗

Graphene Oxide Dysregulates Neuroligin/NLG-1-Mediated Molecular Signaling in Interneurons in Caenorhabditis elegans.Semantic proximity Read ↗

In vivo translocation and toxicity of multi-walled carbon nanotubes are regulated by microRNAs.Semantic proximity Read ↗

Graphene oxide nano-bio interaction induces inhibition of spermatogenesis and disturbance of fatty acid metabolism in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

A dual role of the Wnt signaling pathway during aging in Caenorhabditis elegans.Semantic proximity Read ↗

<i>Drosophila melanogaster</i>as a model organism to study nanotoxicitySemantic proximity Read ↗

Toxicology of carbon nanomaterials in the Caenorhabditis elegans model: current status, characterization, and perspectives for testing harmonizationSemantic proximity Read ↗

Mechanisms and biological impacts of graphene and multi-walled carbon nanotubes on Drosophila melanogaster: Oxidative stress, genotoxic damage, phenotypic variations, locomotor behavior, parasitoid resistance, and cellular immune response.Semantic proximity Read ↗

Feasibility of using a standardized Caenorhabditis elegans toxicity test to assess nanomaterial toxicitySemantic proximity Read ↗

Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in Caenorhabditis elegans.Semantic proximity Read ↗

Identification of interneurons required for the aversive response of Caenorhabditis elegans to graphene oxide.Semantic proximity Read ↗

The nervous system is the major target for Gold nanoparticles: Evidence from RNA sequencing data of <i>C. elegans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.