Article
Effects of low PBP2b levels on cell morphology and peptidoglycan composition in Streptococcus pneumoniae R6.
Journal of bacteriology - 1 Oct 2013
Berg Kari Helene, Stamsås Gro Anita, Straume Daniel, Håvarstein Leiv Sigve
Abstract excerpt
Streptococcus pneumoniae produces two class B penicillin-binding proteins, PBP2x and PBP2b, both of which are essential. It is generally assumed that PBP2x is specifically involved in septum formation, while PBP2b is dedicated to peripheral cell wall synthesis. However, little experimental evidence exists to substantiate this belief. In the present study, we obtained evidence that strongly supports the view that...
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