Article
Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39.
Molecular microbiology - 1 Dec 2013
Land Adrian D, Tsui Ho-Ching T, Kocaoglu Ozden, Vella Stephen A, Shaw Sidney L, Keen Susan K, Sham Lok-To, Carlson Erin E, Winkler Malcolm E
Abstract excerpt
Bacterial cell shapes are manifestations of programs carried out by multi-protein machines that synthesize and remodel the resilient peptidoglycan (PG) mesh and other polymers surrounding cells. GpsB protein is conserved in low-GC Gram-positive bacteria and is not essential in rod-shaped Bacillus subtilis, where it plays a role in shuttling penicillin-binding proteins (PBPs) between septal and side-wall sites of...
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