Article
The characteristic of the synonymous codon usage and phylogenetic analysis of hepatitis B virus.
Genes & genomics - 1 Jul 2020
Qi Xiaoming, Wei Chaojun, Li Yonghong, Wu Yu, Xu Hui, Guo Rui, Jia Yanjuan, Li Zhenhao, Wei Zhenhong, Wang Wanxia, Jia Jing, Li Yuanting, Wang Anqi, Gao Xiaoling
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) infection is a crucial medical issue worldwide. The dependence of HBV replication on host cell machineries and their co-evolutionary interactions prompt the codon usage pattern of viral genes to translation selection and mutation pressure. OBJECTIVE: The evolutionary characteristics of HBV and the natural selection effects of the human genome on the codon usage characteristics...
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