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Article

Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2.

Science translational medicine - 3 Nov 2010

Scott-Van Zeeland Ashley A, Abrahams Brett S, Alvarez-Retuerto Ana I, Sonnenblick Lisa I, Rudie Jeffrey D, Ghahremani Dara, Mumford Jeanette A, Poldrack Russell A, Dapretto Mirella, Geschwind Daniel H, Bookheimer Susan Y

Abstract excerpt

Genetic studies are rapidly identifying variants that shape risk for disorders of human cognition, but the question of how such variants predispose to neuropsychiatric disease remains. Noninvasive human brain imaging allows assessment of the brain in vivo, and the combination of genetics and imag...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21048216
DOI: 10.1126/scitranslmed.3001344
PMCID: PMC3065863

Genes

CNTNAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21048216-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2.PMID 21048216Read ↗

Homozygous Loss of Autism-Risk Gene CNTNAP2 Results in Reduced Local and Long-Range Prefrontal Functional Connectivity.Semantic proximity Read ↗

Homozygous loss of autism-risk gene <i>CNTNAP2</i> results in reduced local and long-range prefrontal functional connectivitySemantic proximity Read ↗

A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism.Semantic proximity Read ↗

Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals.Semantic proximity Read ↗

Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene.Semantic proximity Read ↗

Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2.Semantic proximity Read ↗

Common variation in the autism risk gene CNTNAP2, brain structural connectivity and multisensory speech integration.Semantic proximity Read ↗

Exploring the clinical spectrum of CNTNAP2-related neurodevelopmental disorders: A case series and a literature appraisal.Semantic proximity Read ↗

Associations between the CNTNAP2 gene, dorsolateral prefrontal cortex, and cognitive performance on the Stroop task.Semantic proximity Read ↗

Contact in the genetics of autism and schizophrenia.Semantic proximity Read ↗

Shining a light on CNTNAP2: complex functions to complex disorders.Semantic proximity Read ↗

The Cingulate Structures in Autism Spectrum Disorder: Exploring Its Implication on Social Awareness and the Role of CNTNAP2Semantic proximity Read ↗

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