Article
Brief communication: intraperitoneal galactosamine misdosing as a possible interpretation for responder/nonresponder phenotypes.
Toxicologic pathology - 1 Jan 2014
Brown H Roger, Mellon-Kusibab Kathy, Bertram Rick, Tillman Tony, Arrington-Brown Leigh, Jordan Holly, Gates Lisa, Miller Richard T
Abstract excerpt
Previous reports investigating the mechanisms of galactosamine toxicity have discussed the presence of responders and nonresponders after intraperitoneal (IP) administration of a toxic dose. The incidence of nonresponders has been reported to be as high as 47%. To rule out inadvertent intestinal, solid organ, or subcutaneous injection as at least a partial cause for the variability, we performed midline incisions...
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