Article
Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis.
Journal of proteome research - 1 Nov 2009
Coen Muireann, Want Elizabeth J, Clayton T Andrew, Rhode Cynthia M, Hong Young Shick, Keun Hector C, Cantor Glenn H, Metz Alan L, Robertson Donald G, Reily Michael D, Holmes Elaine, Lindon John C, Nicholson Jeremy K
Abstract excerpt
The amino sugar galactosamine (galN) induces alterations in the hepatic uridine nucleotide pool and has been widely used as a model of human viral hepatitis. Histopathological and clinical chemistry analyses of a cohort of rats following administration of galN revealed extreme interindividual var...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
