Article
Association of CFH and CFB gene polymorphisms with retinopathy in type 2 diabetic patients.
Mediators of inflammation - 1 Jan 2013
Wang Jun, Yang Ming Ming, Li Yan Bo, Liu Guo Dong, Teng Yan, Liu Xiao Min
Abstract excerpt
OBJECTIVES: The complement system is a key component of innate immunity and has been implicated in the pathogenesis of diabetic retinopathy (DR). This study aimed at investigating whether polymorphisms of two genes in the complement pathway, complement factor H (CFH) and complement factor B (CFB), are associated with DR. METHODS: 552 well-defined subjects with type 2 diabetes, consisting of 277 DR patients and...
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