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Article

The involvement of complement factor B and complement component C2 in an Indian cohort with age-related macular degeneration.

Investigative ophthalmology & visual science - 1 Jan 2010

Kaur Inderjeet, Katta Saritha, Reddy Rajeev K, Narayanan Raja, Mathai Annie, Majji Ajit B, Chakrabarti Subhabrata

Abstract excerpt

PURPOSE: Genes involved in the complement cascade such as complement factor B (CFB) and complement component C2 have been implicated in age-related macular degeneration (AMD) worldwide. In continuation of the analysis of CFH and LOC387715/HTRA1, this study was conducted to gain understanding of the role of CFB and C2 in an Indian AMD cohort. METHODS: Single nucleotide polymorphisms in CFB and C2 were screened in...

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Source

Identifiers

PMID: 19696172
DOI: 10.1167/iovs.09-4135

Genes

CFB
CFH
HTRA1

Variants

rs641153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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