Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.

The Journal of general physiology - 1 Sept 2013

Kim Ye-Hyun, Holt Jeffrey R

Abstract excerpt

The hyperpolarization-activated current, Ih, is carried by members of the Hcn channel family and contributes to resting potential and firing properties in excitable cells of various systems, including the auditory system. Ih has been identified in spiral ganglion neurons (SGNs); however, its molecular correlates and their functional contributions have not been well characterized. To investigate the molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Action Potentials
Share to Brain Stem
Share to Evoked Potentials, Auditory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

Share to Reaction Time

Share to RNA, Messenger

Share to Sensory Receptor Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 23980193
DOI: 10.1085/jgp.201311019
PMCID: PMC3753603

Genes

HCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.PMID 23980193Read ↗

Etiology of distinct membrane excitability in pre- and posthearing auditory neurons relies on activity of Cl- channel TMEM16A.Semantic proximity Read ↗

Single-cell mRNA expression of HCN1 correlates with a fast gating phenotype of hyperpolarization-activated cyclic nucleotide-gated ion channels (Ih) in central neurons.Semantic proximity Read ↗

Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.Semantic proximity Read ↗

Hair Cell Mechanotransduction Regulates Spontaneous Activity and Spiral Ganglion Subtype Specification in the Auditory System.Semantic proximity Read ↗

Kv4, Kv2, and Kv3 currents shape intrinsic lateral olivocochlear excitability independent of hair cell dysfunction during development and ageingSemantic proximity Read ↗

Genetic perturbations suggest a role of the resting potential in regulating the expression of the ion channels of the KCNA and HCN families in octopus cells of the ventral cochlear nucleus.Semantic proximity Read ↗

Kv7-type channel currents in spiral ganglion neurons: involvement in sensorineural hearing loss.Semantic proximity Read ↗

Lateral superior olive function in congenital deafness.Semantic proximity Read ↗

h-channels contribute to divergent electrophysiological properties of supragranular pyramidal neurons in human versus mouse cerebral cortexSemantic proximity Read ↗

Physiology and Therapeutic Potential of SK, H, and M Medium AfterHyperPolarization Ion ChannelsSemantic proximity Read ↗

Molecular Specializations Underlying Phenotypic Differences in Inner Ear Hair Cells of Zebrafish and MiceSemantic proximity Read ↗

Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.