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Article

Wnt Pathway Activity in Breast Cancer Sub-Types and Stem-Like Cells

4 Jul 2013

Abstract excerpt

INTRODUCTION: Wnt signalling has been implicated in stem cell regulation however its role in breast cancer stem cell regulation remains unclear. METHODS: We used a panel of normal and breast cancer cell lines to assess Wnt pathway gene and protein expression, and for the investigation of Wnt signalling within stem cell-enriched populations, mRNA and protein expression was analysed after the selection of...

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PMID: 23861811
DOI: 10.1371/journal.pone.0067811

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