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Article

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes.

Gene - 25 Sept 2013

Kalnina Ineta, Zaharenko Linda, Vaivade Iveta, Rovite Vita, Nikitina-Zake Liene, Peculis Raitis, Fridmanis Davids, Geldnere Kristine, Jacobsson Josefin A, Almen Markus S, Pirags Valdis, Schiöth Helgi B, Klovins Janis

Abstract excerpt

Variations in the FTO gene and near the TMEM18 gene are risk factors for common form of obesity, but have also been linked with type 2 diabetes (T2D). Our aim was to investigate the contribution of these variants to risk of T2D in a population in Latvia. Four single nucleotide polymorphisms (SNP) in the first and fourth intronic regions of FTO and one close to TMEM18 were genotyped in 987 patients with T2D and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

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Share to TMEM18 gene

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 23860325
DOI: 10.1016/j.gene.2013.06.079

Genes

FTO
TMEM18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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