Article
Association between FTO gene polymorphisms and type 2 diabetes mellitus, serum levels of apelin and androgen hormones among Iranian obese women.
Gene - 30 Jan 2018
Ghafarian-Alipour Farzaneh, Ziaee Shayan, Ashoori Mohamad Reza, Zakeri Mir Saeid, Boroumand Mohammad Ali, Aghamohammadzadeh Naser, Abbasi-Majdi Maryam, Shool Fatemeh, Asbaghi Navid Sarakhs, Mohammadi Abolghasem, Zarghami Nosratollah
Abstract excerpt
BACKGROUND AND AIMS: Recent studies show that FTO single nucleotide polymorphisms (SNPs) are associated with obesity and type 2 diabetes mellitus (T2DM). On the other hand, many animal models and clinical studies have demonstrated that apelin, an adipocytokine, is related to the obesity and T2DM. Additionally, obese women are at risk of Hyperandrogenemia. So, the aim of this study was to investigate the...
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