Article
Association between MTHFR gene polymorphisms, smoking, and the incidence of vascular dementia.
Asia-Pacific journal of public health - 1 Jul 2013
Jin Pengpeng, Hou Shuangxing, Ding Bojun, Li Deshuai, Liu Lijuan, Li Hongzeng, Li Li, Zhao Gang, Shao Zhongjun, Liu Xuedong
Abstract excerpt
This study investigated the relationship between N5,N10-methylene tetrahydrofolic acid reductase (MTHFR) polymorphisms, smoking, and vascular dementia (VD). Polymerase chain reaction-restriction fragment length polymorphism analysis was used to analyze the frequency of the C/T polymorphism at position 677 of the MTHFR gene in 304 VD patients and 300 control patients with nondementia cerebral infarction. The CC,...
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