Article
Association of ACE I/D gene polymorphism with vascular dementia: a meta-analysis.
Journal of geriatric psychiatry and neurology - 1 Mar 2009
Liu Hua, Liu Ming, Li Wei, Wu Bo, Zhang Shi-hong, Fang Yuan, Wang Yi
Abstract excerpt
BACKGROUND: Vascular dementia is the second common cause of dementia, only second to Alzheimer's disease in later life, and has a greater mortality risk than Alzheimer's disease among the elderly population group. The angiotensin-converting enzyme insertion/deletion polymorphism as a risk factor in vascular dementia has been suggested, but direct evidence from genetic association studies remain inconclusive. We...
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