Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: a meta-analysis.

Journal of the neurological sciences - 15 Jul 2010

Liu Hua, Yang Min, Li Guang-Ming, Qiu Ya, Zheng Jian, Du Xin, Wang Ji-Liang, Liu Ruo-Wei

Abstract excerpt

BACKGROUND/AIMS: Vascular dementia (VaD) is the second common cause of dementia after Alzheimer's disease (AD) in later life. The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism as a risk factor in VaD has been suggested, but direct evidence from genetic association studies remain inconclusive. We performed a meta-analysis pooling data from all relevant studies in order to determine the effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Dementia, Vascular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to MTHFR gene

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Genetic

Share to White People

Source

Identifiers

PMID: 20441995
DOI: 10.1016/j.jns.2010.04.001

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: a meta-analysis.PMID 20441995Read ↗

Genetics of Vascular Dementia: Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Genetic Susceptibility Variants of Vascular Dementia among Asians: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Association between apolipoprotein E gene polymorphism and the risk of vascular dementia: a meta-analysis.Semantic proximity Read ↗

Association between MTHFR gene polymorphisms, smoking, and the incidence of vascular dementia.Semantic proximity Read ↗

Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphism and Alzheimer Disease Risk: a Meta-Analysis.Semantic proximity Read ↗

Association of ACE I/D gene polymorphism with vascular dementia: a meta-analysis.Semantic proximity Read ↗

ApoE gene polymorphism and vascular dementia in Chinese population: a meta-analysis.Semantic proximity Read ↗

Association between the MTHFR gene and Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort.Semantic proximity Read ↗

Apolipoprotein E gene polymorphism in a Chinese population with vascular dementia: a meta-analysis.Semantic proximity Read ↗

The MTHFR C677T polymorphism contributes to increased risk of Alzheimer's disease: evidence based on 40 case-control studies.Semantic proximity Read ↗

MTHFR and ACE gene polymorphisms and risk of vascular and degenerative dementias in the elderly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.