Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Muscular dystrophy in dysferlin-deficient mouse models.

Neuromuscular disorders : NMD - 1 May 2013

Hornsey Mark A, Laval Steven H, Barresi Rita, Lochmüller Hanns, Bushby Kate

Abstract excerpt

Mutations in the dysferlin gene result in the development of a range of early adult-onset, progressive muscular dystrophies, collectively known as the dysferlinopathies. There is currently no effective treatment for these disorders. Several spontaneous and engineered alleles at the mouse dysferlin locus have been isolated and these dysferlin-deficient mouse strains are providing valuable insights into the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Dysferlin
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscular Dystrophies

Share to Muscular Dystrophies, Limb-Girdle

Share to Mutation

Source

Identifiers

PMID: 23473732
DOI: 10.1016/j.nmd.2013.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Muscular dystrophy in dysferlin-deficient mouse models.PMID 23473732Read ↗

Dysferlin and Animal Models for DysferlinopathySemantic proximity Read ↗

Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency.Semantic proximity Read ↗

Dysferlin overexpression in skeletal muscle produces a progressive myopathy.Semantic proximity Read ↗

The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for Treatments.Semantic proximity Read ↗

The Dysferlinopathies Conundrum: Clinical Spectra, Disease Mechanism and Genetic Approaches for TreatmentsSemantic proximity Read ↗

Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.Semantic proximity Read ↗

Common pathological mechanisms in mouse models for muscular dystrophies.Semantic proximity Read ↗

Metabolic dysregulation contributes to the development of dysferlinopathy.Semantic proximity Read ↗

Dysferlin and muscular dystrophy.Semantic proximity Read ↗

The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands.Semantic proximity Read ↗

Enhanced Muscular Dystrophy from Loss of Dysferlin Is Accompanied by Impaired Annexin A6 Translocation after Sarcolemmal Disruption.Semantic proximity Read ↗

The Clinical Outcome Study for dysferlinopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.