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Article

Congenital prothrombin deficiency: an update.

Seminars in thrombosis and hemostasis - 1 Sept 2013

Lancellotti Stefano, Basso Maria, De Cristofaro Raimondo

Abstract excerpt

Prothrombin (factor II [FII]) deficiency is a rare inherited coagulation disorder, having a prevalence of approximately 1 in 2,000,000. Two phenotypes can be distinguished: (1) true hypoprothrombinemia (type I deficiency), characterized by concomitantly low levels of the zymogen antigen; and (2) dysprothrombinemia (type II deficiency), characterized by the normal or near-normal synthesis of a dysfunctional...

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PMID: 23852823
DOI: 10.1055/s-0033-1348948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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