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Article

Management of antithrombin deficiency: an update for clinicians

22 May 2019

Abstract excerpt

Introduction. Antithrombin is a serpin that inhibits multiple procoagulant serine proteases and acts as an endogenous anticoagulant. Thus, congenital antithrombin deficiency constitutes a major thrombophilic state, the most severe so far.Areas covered. In the present work, we globally review the biology, genetics, diagnosis, and management of congenital antithrombin deficiency, and also discuss puzzling questions...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 31116611
DOI: 10.1080/17474086.2019.1611424

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