Article
Inherited antithrombin deficiency: a review.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Nov 2008
Patnaik M M, Moll S
Abstract excerpt
Antithrombin (AT) is a potent inactivator of thrombin and factor Xa and the major inhibitor of blood coagulation. Inherited AT deficiencies are uncommon, with prevalences in the general population between 1 in 500 and 1 in 5000. They are either quantitative (type I) or qualitative (type II). Type II is subdivided into the more common, but less thrombogenic, type IIb deficiency caused by a defect in the...
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