Article
Congenital fibrinogen disorders: an update.
Seminars in thrombosis and hemostasis - 1 Sept 2013
de Moerloose Philippe, Casini Alessandro, Neerman-Arbez Marguerite
Abstract excerpt
Hereditary fibrinogen abnormalities comprise two classes of plasma fibrinogen defects: Type I, afibrinogenemia or hypofibrinogenemia, which has absent or low plasma fibrinogen antigen levels (quantitative fibrinogen deficiencies), and Type II, dysfibrinogenemia or hypodysfibrinogenemia, which shows normal or reduced antigen levels associated with disproportionately low functional activity (qualitative fibrinogen...
Topics
- Afibrinogenemia
- Animals
- Fibrinogen
- Genetic Association Studies
- Genotype
- Hemorrhage
- Humans
- Mutation
- Thrombosis