Article
The optimal design of batteries of short-term tests for detecting carcinogens.
Mutation research - 1 Jan 2000
Heinze J E, Poulsen N K
Abstract excerpt
The optimal design of a battery of short-term tests for detecting carcinogens has been explored by constructing tables describing the theoretical accuracy of various batteries of tests. The analysis has revealed that the expected accuracy of the testing battery is greatly influenced by the design...
Topics
- Animals
- Carcinogens
- Cell Line
- Cell Nucleus
- Chromosome Aberrations
- DNA Replication
- Drug Evaluation, Preclinical
- Escherichia coli
- HeLa Cells
- Humans
- Male
- Mice
- Microsomes, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Rats
- Salmonella typhimurium