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Article

Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension.

Microvascular research - 1 Sept 2004

Mandegar Mehran, Fung Yuan-Cheng B, Huang Wei, Remillard Carmelle V, Rubin Lewis J, Yuan Jason X-J

Abstract excerpt

Pulmonary artery vasoconstriction and vascular remodeling greatly contribute to a sustained elevation of pulmonary vascular resistance (PVR) and pulmonary arterial pressure (PAP) in patients with pulmonary arterial hypertension (PAH). The development of PAH involves a complex and heterogeneous co...

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Source

Identifiers

PMID: 15313118
DOI: 10.1016/j.mvr.2004.06.001

Genes

PAH
PVR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15313118-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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