Article
ESX-1-induced apoptosis is involved in cell-to-cell spread ofMycobacterium tuberculosis
15 Jul 2013
Abstract excerpt
Apoptosis modulation is a procedure amply utilized by intracellular pathogens to favour the outcome of the infection. Nevertheless, the role of apoptosis during infection with Mycobacterium tuberculosis, the causative agent of human tuberculosis, is subject of an intense debate and still remains unclear. In this work, we describe that apoptosis induction in host cells is clearly restricted to virulent M....
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