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Article

FLT3 mutations in myeloproliferative neoplasms: the Beaumont experience.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2013

Williams Lindsay, Kelley Harlan H, Meng Xiuling, Prada Anne, Crisan Domnita

Abstract excerpt

FLT3 is one of the most frequently mutated genes in acute myeloid leukemia. Previous studies have reported FLT3 mutation in as many as 9.2% of myeloproliferative neoplasms (MPNs) and myelodysplastic/myeloproliferative neoplasms (MDS/MPNs), as well as in chronic myelogenous leukemia, that are negative for the JAK2 V617F gene mutation; no FLT3 mutation has been found in JAK2-positive MPNs, suggesting that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23846442
DOI: 10.1097/PDM.0b013e31828564fe

Genes

FLT3
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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