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Article

FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia.

American journal of hematology - 1 Jan 2013

Daver Naval, Strati Paolo, Jabbour Elias, Kadia Tapan, Luthra Raja, Wang Sa, Patel Keyur, Ravandi Farhad, Cortes Jorge, Qin Dong Xiao, Kantarjian Hagop, Garcia-Manero Guillermo

Abstract excerpt

FMS-like tyrosine kinase III (FLT3) mutations occur in one-third of acute myeloid leukemia (AML) patients and predict poor outcome. The incidence and impact of FLT3 in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) is unknown. We conducted a retrospective review to identify WHO MDS and CMML patients with FLT3 mutations at diagnosis. A total of 2,119 patients with MDS and 466 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Leukemia, Myeloid, Acute

Share to Myelodysplastic Syndromes

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Source

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Identifiers

PMID: 23115106
DOI: 10.1002/ajh.23345
PMCID: PMC4085099

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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