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Four Chromosomal Type IV Secretion Systems in Helicobacter pylori: Composition, Structure and Function

10 Jul 2020

Abstract excerpt

The pathogenic bacterium Helicobacter pylori is genetically highly diverse and a major risk factor for the development of peptic ulcer disease and gastric adenocarcinoma in humans. During evolution, H. pylori has acquired multiple type IV secretion systems (T4SSs). These T4SSs represent remarkable molecular transporter machines, often associated with an extracellular pilus structure present in many bacteria,...

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PMID: 32754140
DOI: 10.3389/fmicb.2020.01592

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