Article
Pyruvate oxidase influences the sugar utilization pattern and capsule production in Streptococcus pneumoniae.
PloS one - 1 Jan 2013
Carvalho Sandra M, Farshchi Andisi Vahid, Gradstedt Henrik, Neef Jolanda, Kuipers Oscar P, Neves Ana R, Bijlsma Jetta J E
Abstract excerpt
Pyruvate oxidase is a key function in the metabolism and lifestyle of many lactic acid bacteria and its activity depends on the presence of environmental oxygen. In Streptococcus pneumoniae the protein has been suggested to play a major role in metabolism and has been implicated in virulence, oxidative stress survival and death in stationary phase. Under semi-aerobic conditions, transcriptomic and metabolite...
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