Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL

18 Apr 2013

Abstract excerpt

Chronic lymphocytic leukemia (CLL) -like monoclonal B-cell lymphocytosis (MBL) shares common immunophenotype and cytogenetic abnormalities with CLL, from which it is discriminated by a cutoff value of 5 × 10(9)/L circulating clonal B cells. However, the clonal size in MBL is extremely variable and allows discrimination of two distinct entities (high-count [HC] and low-count [LC]-MBL) based on a cutoff value of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Immunodeficiency and Autoimmune Disorders
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23596047
DOI: 10.1182/blood-2012-12-471698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLLPMID 23596047Read ↗

Different biology and clinical outcome according to the absolute numbers of clonal B‐cells in monoclonal B‐cell lymphocytosis (MBL)Semantic proximity Read ↗

Non-CLL-like monoclonal B-cell lymphocytosis in the general population: prevalence and phenotypic/genetic characteristics.Semantic proximity Read ↗

The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring.Semantic proximity Read ↗

Monoclonal B-cell lymphocytosis: right track or red herring?Semantic proximity Read ↗

Immunologic aspects of monoclonal B-cell lymphocytosis.Semantic proximity Read ↗

Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome.Semantic proximity Read ↗

Combined patterns of IGHV repertoire and cytogenetic/molecular alterations in monoclonal B lymphocytosis versus chronic lymphocytic leukemia.Semantic proximity Read ↗

The molecular map of CLL and Richter's syndromeSemantic proximity Read ↗

General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLLSemantic proximity Read ↗

Monoclonal B-cell lymphocytosis: a reappraisal of its clinical implications.Semantic proximity Read ↗

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLLSemantic proximity Read ↗

Monoclonal B-cell lymphocytosis: a brief review for general clinicians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.