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Article

The MPO -463G>A polymorphism and cancer risk: a meta-analysis based on 43 case-control studies.

Mutagenesis - 1 Jul 2010

Chu Haiyan, Wang Meilin, Wang Miaomiao, Gu Dongying, Wu Dongmei, Zhang Zhizhong, Tang Jialin, Zhang Zhengdong

Abstract excerpt

Myeloperoxidase (MPO) is an endogenous oxidant enzyme that generates reactive oxygen species and plays an important role in the aetiology of cancer. The MPO -463G>A polymorphism influences MPO transcription and has been implicated in cancer risk. However, results from published studies on the association between the MPO -463G>A polymorphism and risk of cancer are conflicting. To derive a more precise estimation...

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Identifiers

PMID: 20418356
DOI: 10.1093/mutage/geq018

Genes

MPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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