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Article

Superparamagnetic iron oxide nanoparticles alter expression of obesity and T2D-associated risk genes in human adipocytes.

Scientific reports - 1 Jan 2013

Sharifi S, Daghighi S, Motazacker M M, Badlou B, Sanjabi B, Akbarkhanzadeh A, Rowshani A T, Laurent S, Peppelenbosch M P, Rezaee F

Abstract excerpt

Adipocytes hypertrophy is the main cause of obesity and its affliction such as type 2 diabetes (T2D). Since superparamagnetic iron oxide nanoparticles (SPIONs) are used for a wide range of biomedical/medical applications, we aimed to study the effect of SPIONs on 22 and 29 risk genes (Based on gene wide association studies) for obesity and T2D in human adipocytes. The mRNA expression of lipid and glucose...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23838847
DOI: 10.1038/srep02173
PMCID: PMC3707025

Genes

GNPDA2
GULP1
INSIG2
KCTD15
LPL
MAF
MTCH2
MTMR9
NAMPT
NEGR1
PFKP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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