Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sestrin2 protects dendrite cells against ferroptosis induced by sepsis.

Cell death & disease - 4 Sept 2021

Li Jing-Yan, Ren Chao, Wang Li-Xue, Yao Ren-Qi, Dong Ning, Wu Yao, Tian Ying-Ping, Yao Yong-Ming

Abstract excerpt

Ferroptosis is a nonapoptotic form of programmed cell death triggered by the accumulation of reactive oxygen species (ROS) depended on iron overload. Although most investigations focus on the relationship between ferroptosis and cancer, neurodegenerative diseases, and ischemia/reperfusion injury, research on ferroptosis induced by immune-related inflammatory diseases, especially sepsis, is scarce. Sestrin2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activating Transcription Factor 4
Share to Cecum
Share to Ferroptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity

Share to Ligation

Share to Peroxidases

Share to Protective Agents

Share to Transcription Factor CHOP

Source

Open in PubMed Open full text

Identifiers

PMID: 34482365
DOI: 10.1038/s41419-021-04122-8
PMCID: PMC8418614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sestrin2 protects dendrite cells against ferroptosis induced by sepsis.PMID 34482365Read ↗

Identification of Ferroptosis-related genes in sepsis-induced acute respiratory distress syndromeSemantic proximity Read ↗

Ferroptosis, Pyroptosis and Necroptosis-related Genes in Sepsis-induced Acute Respiratory Distress Syndrome and Immune InfiltrationSemantic proximity Read ↗

Identification of ZIP8-induced ferroptosis as a major type of cell death in monocytes under sepsis conditionsSemantic proximity Read ↗

Diagnostic and Predictive Values of Ferroptosis-Related Genes in Child SepsisSemantic proximity Read ↗

Integration of Transcriptomic and Single-Cell Data to Uncover Senescence- and Ferroptosis-Associated Biomarkers in SepsisSemantic proximity Read ↗

Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validationSemantic proximity Read ↗

The Emerging Role of Ferroptosis in Sepsis, Opportunity or Challenge?Semantic proximity Read ↗

Identification of ferroptosis-related genes in male mice with sepsis-induced acute lung injury based on transcriptome sequencingSemantic proximity Read ↗

Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlationSemantic proximity Read ↗

Mitophagy and Ferroptosis in Sepsis-Induced ALI/ARDS: Molecular Mechanisms, Interactions and Therapeutic Prospects of Medicinal PlantsSemantic proximity Read ↗

Identification of WIPI1 as A Potential Ferroptosis-Related Biomarker in Sepsis and Validation in CLP Mice Model.Semantic proximity Read ↗

LPIN1 Is a Regulatory Factor Associated With Immune Response and Inflammation in SepsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.