Article
Whole genome sequencing.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Ng Pauline C, Kirkness Ewen F
Abstract excerpt
Whole genome sequencing provides the most comprehensive collection of an individual's genetic variation. With the falling costs of sequencing technology, we envision paradigm shift from microarray-based genotyping studies to whole genome sequencing. We review methodologies for whole genome sequencing. There are two approaches for assembling short shotgun sequence reads into longer contiguous genomic sequences. In...
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