Article
Allogenicity of human cardiac stem/progenitor cells orchestrated by programmed death ligand 1.
Circulation research - 1 Feb 2013
Lauden Laura, Boukouaci Wahid, Borlado Luis R, López Itziar Palacios, Sepúlveda Pilar, Tamouza Ryad, Charron Dominique, Al-Daccak Reem
Abstract excerpt
RATIONALE: Transplantation of allogeneic cardiac stem/progenitor cells (CPC) in experimental myocardial infarction promoted cardiac regeneration and improved heart function. Although this has enhanced prospects of using allogeneic CPC for cardiac repair, the mechanisms regulating the behavior of these allogeneic cells, which are central to clinical applications, remain poorly understood. OBJECTIVE: T cells...
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