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Article

FGF14 regulates presynaptic Ca2+ channels and synaptic transmission.

Cell reports - 11 Jul 2013

Yan Haidun, Pablo Juan L, Pitt Geoffrey S

Abstract excerpt

Fibroblast growth factor homologous factors (FHFs) are not growth factors, but instead bind to voltage-gated Na+ channels (NaV) and regulate their function. Mutations in FGF14, an FHF that is the locus for spinocerebellar ataxia 27 (SCA27), are believed to be pathogenic because of a dominant-negative reduction of NaV currents in cerebellar granule cells. Here, we demonstrate that FGF14 also regulates members of...

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Source

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Identifiers

PMID: 23831029
DOI: 10.1016/j.celrep.2013.06.012
PMCID: PMC3736584

Genes

FGF14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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