Article
Mutant spectrum of dengue type 1 virus in the plasma of patients from the 2006 epidemic in South China.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Nov 2013
Tu Zeng, He Yong-lin, Lu He, Xu Lei, Yang Zhi-bang, Yang Chun, Chen Wei-jun
Abstract excerpt
The aim of the present study was to explore the mutant spectrum of dengue type 1 virus (DENV-1) within individuals during the 2006 dengue epidemic in South China. A 513-bp fragment including most of domain III of the envelope (E) gene was amplified directly from clinical samples, then cloned and sequenced. A total of 89 clones from six patients (range 11-17 clones per patient) were sequenced. Genetic diversity...
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