Dengue in China: Comprehensive Phylogenetic Evaluation Reveals Evidence of Endemicity and Complex Genetic Diversity.

doi:10.4269/ajtmh.15-0546

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Article

Dengue in China: Comprehensive Phylogenetic Evaluation Reveals Evidence of Endemicity and Complex Genetic Diversity.

The American journal of tropical medicine and hygiene - 1 Jan 2016

Chen Rubing, Han Guan-Zhu

Abstract excerpt

Despite the increasing threat of dengue outbreaks in China, it is still considered as an imported disease and its introduction and/or circulation patterns remain obscure. On the basis of the most extensive phylogenetic analysis to date, we showed highly complex genetic diversity of dengue viruses (DENVs) in south China with up to 20 different clades/lineages from multiple serotypes co-circulating in the same...

Topics

China
Dengue
Dengue Virus
Endemic Diseases
Genetic Variation
Global Health
Humans
Phylogeny

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Identifiers

PMID: 26458780
DOI: 10.4269/ajtmh.15-0546
PMCID: PMC4710430

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