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Molecular characterization and genotype shift of dengue virus strains between 2001 and 2014 in Guangzhou.

Epidemiology and infection - 1 Mar 2017

Jiang L Y, Jing Q L, Liu Y, Cao Y M, Su W Z, Biao D, Yang Z C

Abstract excerpt

We studied the evolution, genotypes, and the molecular clock of dengue virus serotype 1 (DENV-1), between 2001 and 2014 in Guangzhou, China. The analysis of the envelope (E) gene sequences of 67 DENV-1 strains isolated in Guangzhou, together with 58 representative sequences downloaded from NCBI, have shown shifts in viral genotypes. The genotype changed several times, from genotype I to IV in 2002, from IV to I...

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PMID: 27919298
DOI: 10.1017/S0950268816002429
PMCID: PMC5426331

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