Article
Genotypic and phenotypic heterogeneity in the U3R region of HIV type 1 subtype C.
AIDS research and human retroviruses - 1 Jan 2014
Mates Jessica M, Kumar Surender B, Bazan Jose, Mefford Megan, Voronkin Igor, Handelman Samuel, Mwapasa Victor, Ackerman William, Janies Daniel, Kwiek Jesse J
Abstract excerpt
Approximately 20% of all HIV-1 mother-to-child transmission (MTCT) occurs in utero (IU). In a chronic HIV infection, HIV-1 exists as a complex swarm of genetic variants, and following IU MTCT, viral genomic diversity is restricted through a mechanism that remains to be described. The 5' U3R region of the HIV-1 long terminal repeat (LTR) contains multiple transcription factor (TF) binding sites and regulates viral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
